Medications and Dosage

Anti Androgens

Two anti-androgen options seem to be more widely used than others. These are:

  • Cyproterone Acetate at 100mg – 150mg daily, taken orally. This one seems to carry an increased risk of depressive symptoms, and should this side effect occur, the medication is often changed.
  • Spironolactone – 100mg- 200mg daily, taken orally. This one might be a good option if you have high blood pressure or are concerned about blood clots or venous thromboembolism as it is a potassium-sparing diuretic.

Other options include:

  • Medroxyprogesterone – 5mg – 10mg daily, taken orally, or 150mg monthly via intramuscular injection.
  • Nilutamide – 300mg daily, taken orally. This one can cause androgen production in rare cases, so it is usually not the first choice.
  • Flutamide – 250mg three times daily, taken orally. This one can also potentially cause androgen production, so it is not the first choice.

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